2C-E

In brief

A 2C-series phenethylamine known as intense and deep, very visual and bodily, with a long, demanding comeup. Narrow margin between doses.

Same as the 2C series: fast tolerance, resetting in a few days to two weeks, cross-tolerant with the psychedelic phenethylamines and tryptamines.

MAOIs contraindicated. Avoid stimulants and other serotonergics (cardiac load, overstimulation). Lithium and tramadol: seizure risk.

Major risks, not exhaustive; when in doubt, check a harm-reduction resource.

Route : oral · onset ~1 h · peak ~2 h · duration ~8 h

Indicative orders of magnitude; they vary with dose, route and individual.

No La Honda note on this substance yet.

Synthesis

Synthesis article to be written (phase 2): pharmacology, phenomenology, mechanisms, harm reduction, sources.